ʻO ka sodium Sulfadiazine kahi lāʻau antibiotic sulfonamide medium-acting e loaʻa ana nā hopena antibacterial i nā hua bacteria Gram-positive a me Gram-negative. Loaʻa iā ia nā hopena antibacterial ma luna o Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, Neisseria gonorrhoeae, Neisseria meningitidis, a me Haemophilus influenzae. Eia kekahi, he mea ikaika ia e kū'ē iā Chlamydia trachomatis, Nocardia asteroides, Plasmodium, a me Toxoplasma in vitro. ʻO ka hana antibacterial o kēia huahana e like me ka sulfamethoxazole. Eia nō naʻe, i nā makahiki i hala iho nei, ua piʻi aʻe ka pale ʻana i ka maʻi bacteria i kēia huahana, ʻoi aku ka Streptococcus, Neisseria, a me Enterobacteriaceae.