Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate: Nā waiwai a me ka hana.

Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylateHe hui kemika me ke kumu mole C9H6F2O4 a me ka helu CAS 773873-95-3. ʻIke ʻia ia e kekahi mau huaʻōlelo like, e like me methyl 2,2-difluoro-1,3-benzodioxole-5-carboxylate, 2,2-difluorobenzodioxole-5-carboxylic acid methyl ester, a me EOS-61003. Aia ia i ka papa o nā pūhui heterocyclic me nā hetero-atoms oxygen wale nō.

Ke hoʻokiʻekiʻe nei i ka maʻemaʻe o 98% ka liʻiliʻi, ʻo kēia pūhui lāʻau lapaʻau he hopena versatile no nā ʻoihana e like me nā lāʻau lapaʻau, agrochemical, a me ka noiʻi.

Ma kēiaʻatikala, e wehewehe mākou i nā waiwai huahana kiko'ī a me ka hana o methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate, e pili ana i ka ʻikepili i loaʻa.

Na Waiwai Kino a Kimia

ʻO ka Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate he wai kala ʻole a ʻeleʻele melemele a paʻa paha, e pili ana i ka mahana a me ka maʻemaʻe. He 216.14 g/mol kona kaumaha a me 1.5±0.1 g/cm3. He 227.4±40.0 °C kona wahi paila ma 760 mmHg a he 88.9±22.2 °C. He haʻahaʻa haʻahaʻa kaomi mahu o 0.1±0.4 mmHg ma 25°C a me ka wai haʻahaʻa solubility o 0.31 g/L ma 25°C. Loaʻa iā ia ka waiwai P log o 3.43, e hōʻike ana he ʻoi aku ka hoʻoheheʻe ʻana i nā mea hoʻoheheʻe organik ma mua o ka wai.

ʻO ke ʻano o ka methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate he apo benzene i hui pū ʻia me ke apo 1,3-dioxole, me ʻelua mau ʻātoma fluorine a me kahi hui carboxylate i hoʻopili ʻia i ke apo benzene. . ʻO ka heleʻana o nā'āpana fluorine e hoʻonui i ka paʻa a me ka hana hou o ka pūhui, a me kona lipophilicity a me ka bioavailability. Hiki i ka hui carboxylate ke hana ma ke ʻano he hui haʻalele a i ʻole he nucleophile i nā ʻano hopena like ʻole. Hiki i ke apo 1,3-dioxole ke hana ma ke ʻano he glycol masked a i ʻole he dienophile i nā hopena cycloaddition.

Ka palekana a me ka lawelawe ʻana

Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate ua hoʻokaʻawale ʻia ma ke ʻano he mea weliweli e like me ka Globally Harmonized System of Classification and Labeling of Chemicals (GHS). Loaʻa iā ia nā ʻōlelo pilikua a me nā ʻōlelo hoʻomalu:

• H315: Hoʻopilikia i ka ʻili

• H319: Hoʻopilikia i ka maka

• H335: Hiki ke hoʻoulu i ka hanu

• P261: Hōʻalo i ka hanu ʻana i ka lepo/fume/gas/noe/huhū/pepa

• P305+P351+P338: INA I KA MAKA: Holoi akahele me ka wai no kekahi mau minuke. Wehe i nā leka pili, inā aia a maʻalahi ke hana. E hoʻomau i ka holoi ʻana

• P302+P352: INA MA KA ILI: Holoi me ke kopa a me ka wai

ʻO nā mea kōkua mua no ka methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate penei:

• Inhalation: Inā inhaled, hoʻoneʻe i ka mea maʻi i ka ea hou. Inā paʻakikī ka hanu, hāʻawi i ka oxygen. Inā ʻaʻole hanu, hāʻawi i ka hanu ʻana. E kiʻi i ka lāʻau lapaʻau

• Hoʻopili i ka ʻili: Wehe i nā lole i haumia a holoi pono i ka ʻili me ke kopa a me ka wai. Inā ʻoluʻolu ʻole ʻoe, e ʻimi i ka lāʻau lapaʻau

• Hoʻopili maka: E hoʻokaʻawale i nā lihilihi a holoi me ka wai kahe a i ʻole ka paʻakai maʻamau. E ʻimi koke i ka lāʻau lapaʻau

• Ingestion: Kāmu, mai hoʻoulu i ka luaʻi. E ʻimi koke i ka lāʻau lapaʻau

ʻO nā ana pale ahi no ka methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate penei:

• Mea ho'opau kinai: E kinai i ke ahi me ka noe wai, ka pauka malo'o, ka hu'a a i'ole ka mea ho'opau kalapona. E hōʻalo i ka hoʻohana ʻana i ka wai kahe pololei e kinai i ke ahi, hiki ke hoʻopā ʻia ka wai ʻā a hoʻolaha i ke ahi.

• Nā pōʻino kūikawā: ʻAʻohe ʻikepili i loaʻa

• Nā hana mālama ahi a me nā hana pale: Pono nā limahana ahi e ʻaʻahu i nā mea hanu ea, e ʻaʻahu i nā lole ahi piha, a e hakakā i ke ahi ma luna o ka makani. Inā hiki, e hoʻoneʻe i ka ipu mai ke ahi i kahi ākea. Pono e hoʻokuʻu koke ʻia nā pahu ma kahi o ke ahi inā ʻeleʻele a hoʻopuka paha ke kani mai ka mea hoʻopakele palekana. E hoʻokaʻawale i ke kahua ulia a pāpā i nā limahana pili ʻole mai ke komo ʻana. Hoʻopaʻa a mālama i ka wai ahi e pale ai i ka pollution kaiapuni

Ka hopena

ʻO ka Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate kahi mea koʻikoʻi ma waena o ka synthesis lāʻau lapaʻau, ka hana ʻana i nā huahana pale hua, a me ka noiʻi ʻepekema. He ʻano ʻokoʻa kona me nā ʻāpana fluorine ʻelua a me kahi hui carboxylate i hoʻopili ʻia i kahi apo benzodioxole, e hāʻawi ana i ka paʻa, reactivity, lipophilicity, a me ka bioavailability i ka pūhui. He haʻahaʻa ka hoʻoheheʻe wai a me ke kaomi mahu, a me ka helu hoʻolapalapa haʻahaʻa a me ka helu uila. Hoʻokaʻawale ʻia ʻo ia ma ke ʻano he mea pōʻino a pono e mālama pono a mālama pono. Loaʻa iā ia nā noi i nā ʻoihana like ʻole, e like me ka lāʻau lapaʻau, agrochemical, noiʻi, a me nā mea ʻē aʻe.

No ka ʻike hou aku a i ʻole nā ​​nīnau, e ʻoluʻolukāhea iā mā˚ou:

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