ʻO Sulfamethazine

ʻO Sulfadiazine kahi lāʻau antibiotic sulfanilamide me ka spectrum antibacterial like me ka sulfadiazine. Loaʻa iā ia nā hopena antibacterial ma nā bacteria enterobacteriaceae e like me non-zymogenic Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, etc. Neisseria gonorrhoea, Neisseria meningitidis a me Haemophilus influenzae. Eia nō naʻe, ua piʻi aʻe ka pale ʻana o ka bacteria i ka huahana, ʻoi aku ka nui o streptococcus, Neisseria a me Enterobacteriaceae bacteria. ʻO Sulfonamides nā mea bacteriostatic ākea ākea, e like me ka p-aminobenzoic acid (PABA), hiki ke hoʻokūkū i ka dihydrofolate synthetase i loko o ka bacteria, no laila e pale aku ai i ka PABA mai ka hoʻohana ʻana i mea maka e synthesize folate i koi ʻia e ka bacteria a hōʻemi i ka nui o ʻo ka tetrahydrofolate e hoʻoikaika kino ana. ʻO ka hope he mea koʻikoʻi no ka synthesis o nā purines, thymidine nucleosides a me ka deoxyribonucleic acid (DNA), no laila ke kāohi nei i ka ulu a me ka hana hou ʻana o ka bacteria.