ʻO Sulfamethazine
ʻAno kino a me kemika
Māmā: 1.392g/cm3
Kahi hehee: 197°C
Puni paila: 526.2ºC
Kekahi uila: 272.1ºC
ʻAno: ka pauka crystalline keʻokeʻo
Solubility: aneane hiki ʻole ke hoʻoheheʻe ʻia i ka wai, ʻaʻole hiki ke hoʻoheheʻe ʻia i ka etera, hiki ke hoʻoheheʻe ʻia i loko o ka dilute acid a i ʻole dilute alkali solution.
ʻO Sulfadiazine kahi lāʻau antibiotic sulfanilamide me ka spectrum antibacterial like me ka sulfadiazine. Loaʻa iā ia nā hopena antibacterial ma nā bacteria enterobacteriaceae e like me non-zymogenic Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, etc. Neisseria gonorrhoea, Neisseria meningitidis a me Haemophilus influenzae. Eia nō naʻe, ua piʻi aʻe ka pale ʻana i ka maʻi bacteria i ka huahana, ʻoi aku ka nui o streptococcus, Neisseria a me Enterobacteriaceae bacteria. ʻO Sulfonamides nā mea bacteriostatic ākea ākea, e like me ka p-aminobenzoic acid (PABA), hiki ke hoʻokūkū i ka dihydrofolate synthetase i loko o ka bacteria, no laila e pale aku ai i ka PABA mai ka hoʻohana ʻana i mea maka e synthesize folate i koi ʻia e ka bacteria a hōʻemi i ka nui o ʻo ka tetrahydrofolate e hoʻoikaika kino ana. He mea koʻikoʻi ka hope no ka synthesis o nā purines, thymidine nucleosides a me ka deoxyribonucleic acid (DNA), no laila ke kāohi nei i ka ulu a me ka hana hou ʻana o ka bacteria.
Hoʻohana nui ʻia ia no nā maʻi maʻalahi i hoʻokumu ʻia e ka maʻi bacteria maʻalahi, e like me ka maʻi maʻi maʻalahi maʻalahi o ka urinary tract, acute otitis media a me ka maʻi ʻili palupalu.