2-methyl-5-nitroimidazole
ʻIke kumu:
Ka inoa kemika: 2-methyl-5-nitroimidazole;
inoa Pelekane: 2-Methyl-5-nitroimidazole;
Helu CAS: 88054-22-2
Huina mole: C4H5N3O2
Kaumaha molekula: 127.1
Helu EINECS: 618-108-7
Kumu hoʻolālā:
Nā ʻāpana pili: nā mea maka; Nā mea waena lāʻau lapaʻau; ʻO nā mea lāʻau lapaʻau.
Māmā:1.4± 0.1g /cm3
Puni paila: 399.5±15.0 °C ma 760 mmHg
Puni hehee :252-254ºC
Lahi uila:195.4±20.4 °C
Nuipa pololei :127.038177
PSA:74.50000 LogP:-0.10
Nānā: Keʻokeʻo keʻokeʻo
Pumi mahu:0.0±0.9 mmHg ma 25°C
Hōʻike hoʻohālikelike:1.592
Nā kūlana mālama: hoʻopaʻa ʻia i kahi wahi maloʻo a maloʻo o 0-6 ºC
Paʻa: ʻaʻole ia e decompose ke hoʻohana ʻia a mālama ʻia e like me nā lula.
| kikoʻī | hui | maʻamau |
| Ka nana aku | E like me ka pauka keʻokeʻo a melemele paha | |
| Maʻiʻo | % | ≥99% |
| Mākū | % | ≤0.3 |
| Sulphate | % | ≤0.3 |
Hoʻohana nui ʻia i ka synthesis o metronidazole, dimetazole a me nā lāʻau lapaʻau ʻē aʻe.
Loaʻa ia ma ka nitratation o 2-methylimidazole. E hoʻokomo i ka waikawa sulfuric, 2-methylimidazole a me ka sodium sulfate i loko o ka ipu hao, hoʻoulu a wela, hoʻohui i ka waikawa nitric ma 150-160 ℃, hoʻohui, e hahai i ka hopena o ka pahu no 1 hola. Wehe i ka mahana i 140 ℃ ma lalo, ma hope o ka hoʻohui ʻana i ka wai me ka wai amonia e hoʻoponopono i ka pH i 3.5-4, crystallization. E kānana, holoi i ke kūʻokoʻa, maloʻo, 2-methyl-5-nitroimidazole.
ʻeke pepa kraft 25k a i ʻole ʻeke i ulana ʻia (58 × 110) i hoʻopaʻa ʻia me ka ʻeke ʻeke, 250kg ʻeke pahu pahu (100 × 80); E like me nā koi o ka mea kūʻai aku;
Hoʻopaʻa ʻia ka mālama ʻana, mālama ʻia i loko o kahi hale kūʻai maloʻo, ʻeleʻele, maloʻo, mālama a me ka lawe ʻana e māmā, e pale aku i ka pōʻino a me ka makū, pāpā loa ʻia me nā lāʻau i hui ʻia.
Kaʻina hana: Loaʻa ʻia e ka nitratation o 2-methylimidazole. E hoʻokomo i ka waikawa sulfuric, 2-methylimidazole a me ka sodium sulfate i loko o ka ipu hao, hoʻoulu a wela, hoʻohui i ka waikawa nitric ma 150-160 ℃, hoʻohui, e hahai i ka hopena o ka pahu no 1 hola. Wehe i ka mahana i 140 ℃ ma lalo, ma hope o ka hoʻohui ʻana i ka wai me ka wai amonia e hoʻoponopono i ka pH i 3.5-4, crystallization. E kānana, holoi i ke kūʻokoʻa, maloʻo, 2-methyl-5-nitroimidazole.
